RNA Details
Disease Name
conjunctival fibrosis
Tissue
eye
RNA Symbol
mir-200a
RNA ID
RNA Type
miRNA
Alteration Pattern
dna methylation
Species
homo sapiens
Detection Methods
qRT-PCR; immunoblot; immunocytochemistry etc.
Target
NA
Pathway
NA
PubMed ID
Title
DNA methylation of miR-200 clusters promotes epithelial to mesenchymal transition in human conjunctival epithelial cells
Year
2020
Function
"Our results indicate that dna demethylation of promoters of mir-200 loci is critically important for stopping and reverting the emt in human conjunctival epithelial cells, suggesting the potential for the development of novel epigenetic-based therapeutic strategies for treating conjunctival conditions associated with emt."